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BioSorter Multi-Range Cytometer

Accessory Modules

A variety of optional modules are available to add specific enhanced capabilities to your BioSorter system including choices of lasers, larger sample cups and an auto-sampler.

FOCAs (Fluidic and Optics Core Assemblies)

Depending on your application(s) you can choose from a range of FOCAs including 250, 500, 1000 and 2000 micron as well as metal-free. For more details please see the main BioSorter pages above.

 

Laser Choices

BioSorter can accommodate up to four excitation lasers. The 488nm is standard but many customers also add a 405nm, 445nm, 561nm, 640nm or 660nm laser. Please inquire if your research requires a different excitation wavelength. These lasers can either be added as part of the initial factory build or later as a field upgrade.

 

Sample Cups

Samples are introduced via a standard 50 ml conical tube (40 ml working volume) with suspended stirrer. For larger samples optional 750 ml and 1500 ml stirred sample cups are available.

 

LP Sampler™ (Large Particle Sampler)

The LP Sampler is the only automated sample introduction system designed specifically for gentle handling of large, fragile objects such as.

  • delicate cells/clusters (stem cell clusters, neurospheres, tumor spheroids)
  • viable small multicellular model organisms (nematodes, Drosophila, zebrafish larvae)
  • beads used as micro-carriers for clonal libraries
  • seeds and fragile plant tissue


This autosampler is ideal for objects ranging from 10 to 1500 microns in diameter. It is capable of gently aspirating those samples from multiwell plates or a petri dish and delivering them intact to Union Biometrica’s COPAS FP™ BioSorter® or VAST BioImager™ systems. It has the flexibility to handle a variety of standard or deep well plates including 24, 96 and 384.

Rotating Sample Chamber

The Rotating Sample Introduction Chamber gently agitates samples without using mechanical stirring.  Both 5 mL and 10 mL sample chambers are included. Use on a BioSorter instrument with either a 250 or 500 µm FOCA.  The Rotating Sample Chamber is designed specifically for

  • handling extremely delicate samples (adipocytes, plant protoplasts, etc.)
  • samples that tend to either float or sink in a sample cup with normal stirring-type agitation. Chamber can be used with 250 & 500 micron flow cells / FOCAs (order separately).

Typical use with a mouse adipocyte preparation enables analyzing 100 objects/second and dispensing intact adipocytes constituting 10% of the preparation.