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Union Biometrica, Inc. to do a live VAST BioImager™ demonstration at the Collaborative Workshop on Aquatic Models and 21st Century Toxicology in Raleigh, NC

Zebrafish play an important role in toxicology screening as evidenced by the 77 zebrafish based abstracts at the Society of Toxicology’s 53rd Annual Meeting and ToxExpo™ in Phoenix, AZ March 23-27, 2014.

VAST BioImager meets the growing needs of toxicology researchers studying zebrafish by allowing zebrafish handling and cellular-resolution imaging tasks to be automated. The system mechanically loads each larva into a capillary, positions it laterally, and then rotates it in the field of view of the on-board camera for organ level imaging. Alternately the VAST can be mounted on a high resolution upright microscope for high content bright field or fluorescent imaging at the cellular level.  Our LP Sampler can be added to the system to gently aspirate larvae from multi-well plates of many different formats such as 24-, 96-, 384-well and deliver them one at a time to VAST for imaging.  This allows for increased throughput of high content assays and screens.  For more detail and to see a video on VAST go to: http://www.unionbio.com/vast/

 

About Union Biometrica, Inc.

Large Particle Flow Cytometry for Gentle Sorting of Model Organisms -- Union Biometrica offers tools for high throughput research of model organism such as early stages of zebrafish, C.elegans, Drosophila embryos and larvae, sea urchin embryos, Xenopus eggs and embryos, Daphnia, various marine larvae and zooplankton. We provide Large Particle Flow Cytometers (COPAS™ and BioSorter®) for objects that are too large / too fragile for traditional cytometers and offer an alternative to manual sorting. These systems analyze and sort objects based on size and fluorescent parameters. Automating this process offers increased speed, sensitivity, quantification, and repeatability of experiments. 

Background publications on the VAST BioImager:

        1.     Nature Methods, 2010, 7 600-601 and 634-636, Carlos Pardo-Martin, Tsung-Yao Chang, Bryan Kyo Koo, Cody L Gilleland, Steven C Wasserman and Mehmet Fatih Yanik  http://www.ncbi.nlm.nih.gov/pubmed/20639868

        2.     Lab Chip, 2012, 12 711-716, Tsung-Yao Chang, Carlos Pardo-Martin, Amin Allalou, Carolina Wählby and Mehmet Fatih Yanik http://pubs.rsc.org/en/content/articlelanding/2012/lc/c1lc20849g

 

Publications related to the VAST BioImager can be view at:

Peer reviewed journal papers referencing the sorting of zebrafish using our COPAS and BioSorter instruments can be viewed using the link below.

 

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